HOPE Thoracic repository

Welcome to the HOPE Thoracic Repository, a resource for heart and lung transplant programs interested in launching pilot programs for HIV D+/R+ transplants (“HOPE transplants”).

Background

Investigators across the U.S. are preparing for a nationwide trial of HIV D+/R+ transplants, planned for launch in 2027.In the meantime, updated federal laws now allow centers to establish their own independent HIV D+/R+ heart transplant programs.

Join the Network

To join our listserv, please email: mprizzi1 at jhu dot edu or toidcrc at jh dot edu.

Available Resources

This site provides sample protocols and paperwork to help your site get started. All materials are freely downloadable, including:

We can also connect you with members of our consortium to help establish a Data and Safety Monitoring Board (DSMB) if needed.

Once your institution has IRB approval, you can apply for a UNOS variance as per the process delineated here: https://www.hrsa.gov/sites/default/files/hrsa/optn/21_hope-act-variance-request-form.pdf

We hope to update this page with information about a future funded trial soon!

Contact

For additional questions, please contact:
Vagish Hemmige — vahemmig at montefiore dot org